ASeq Newsletter

ASeq Newsletter

Protein Sequencing...

Mar 25, 2026
∙ Paid

A little while ago I wrote about the future of protein sequencing.

We’ve had a couple of interesting papers published since then:

  • This paper, on a newish peptide → DNA readout.

  • Highly Parallel Mass Spec.

  • Parallel Squared FRO.

Most of this comes via the Discord! (Many Thanks!)

Peptide → DNA Readout

The approach converts peptides cyclicly using Edman degradation and antibody recognizers. So you end up with DNA that looks like this:

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