Protein Sequencing...
A little while ago I wrote about the future of protein sequencing.
We’ve had a couple of interesting papers published since then:
This paper, on a newish peptide → DNA readout.
Parallel Squared FRO.
Most of this comes via the Discord! (Many Thanks!)
Peptide → DNA Readout
The approach converts peptides cyclicly using Edman degradation and antibody recognizers. So you end up with DNA that looks like this:
